Lightning Learning: Kawasaki Disease

Lightning Learning: Kawasaki Disease

“Kawasaki Disease is a vasculitis affecting medium-sized arteries and is the leading cause of acquired heart disease in the developed world.”
— advice is based on local guidelines & procedures

STOP!

Kawasaki Disease is a vasculitis affecting medium-sized arteries.

Emergency clinicians should consider Kawasaki disease in kids with prolonged fever, as prompt management significantly decreases the risk of serious cardiac sequelae.

Diagnostic criteria: 5-day fever PLUS four of the following…

  • Bilateral conjunctivitis

  • Cervical lymph node >1.5cm

  • Polymorphous exanthem

  • Cracked lips/strawberry tongue

  • Erythema/oedema/peeling of the hands/feet

Other features include BCG scar inflammation, raised CRP and irritability without CNS infection.

Beware: diagnosis can be made before Day 5 of fever if clinical signs suggestive. Also if just 2-3 criteria present, consider incomplete Kawasaki.

LOOK

Kawasaki Disease is the leading cause of acquired heart disease in the developed world. It affects children under the age of 6 years old with severe disease often associated with children under 1 year old. Treatment is with high-dose aspirin, IV immunoglobulin & PPI.

Complications include:

  • Coronary aneurysms (causing thrombosis, MI and tamponade)

  • Myocarditis

  • Bleeding (due to aspirin)

Consider echo EARLY in diagnosis!

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